Severe sepsis and septic shock are life-threatening disorders and constitute the major cause of mortality in critically ill patients. Profound cellular dysfunction, sepsis-induced tissue hypoperfusion,and profound lactic acidosis characterize septic shock. Perhaps nowhere else is a comprehensive understanding of physiology and pathophysiology as critical to the bedside nurse. It facilitates understanding of the clinical presentation and appreciation of the treatment modalities.
This seminar presents state-of-the art information and includes both an update on pathophysiology and a detailed discussion of medical, surgical and pharmacological management of these complex patients. An overview of hemodynamic monitoring and newer methods of assessing preload responsiveness is also included.
Barbara Clark Mims,
MSN, RN-BC, CCRN-K