Objectives

	List the six types of shock and two common causes for each.
	Identify the important assessment parameters for each type of shock.
	Discuss the role that endothelial dysfunction has in the pathogenesis of severe shock.
	State five biological mediators and indicate the prominent physiological role of each.
	Outline the typical course of sequential organ dysfunction and failure common after severe shock.
	Given a case history and assessment parameters, score a patient using the MODS scoring system.
	State the mechanism of action for Xigris and why it is used with septic shock patients.
	List four therapies that might be used to improve O₂ delivery and tissue perfusion in the shock patient.